Novak Djokovic renews his 16-year rivalry with Rafael Nadal at the French Open on Tuesday with a semi-final spot at stake and where victory for the world number one could end the 13-time champion's Roland Garros career.

Nadal, who turns 36 on Friday, puts his record of 109 wins and just three losses in Paris since his title-winning debut in 2005 on the line against the defending champion.

The Spaniard was taken to five sets for only the third time at the tournament by 21-year-old Felix Auger-Aliassime in the fourth round.

In the immediate aftermath of that victory, Nadal admitted that not only was this year's French Open at stake but possibly his entire playing future.

"I know my situation, and I accept it," said Nadal, who arrived in Paris unsure if he would be able to take part after suffering a recurrence of a chronic foot injury which has plagued him for most of his career.

"I am just enjoying the fact that I am here for one more year. And being honest, every match that I play here, I don't know if it's going to be my last at Roland Garros."

Overall, Djokovic leads Nadal 30-28 since their first career meeting at the 2006 French Open.

Nadal has a 19-8 edge on clay and has won seven of the pair's nine meetings in Paris.

Djokovic, however, came out on top in the semi-finals at Roland Garros in 2021 on his way to a second title.

- Night fears -
That defeat took a physical toll on Nadal who then skipped Wimbledon, the Olympics and the US Open.

With Djokovic deported from Melbourne on the eve of the Australian Open, Nadal seized the opportunity to claim a record-setting 21st Grand Slam title, breaking a tie with Djokovic and Roger Federer.

Both men are playing in the quarter-finals at Roland Garros for the 16th time.

Djokovic has reached the last-eight with ease. He has won 22 sets in a row, a run stretching back to his Italian Open triumph in Rome.

"I'm glad that I didn't spend too much time on the court up to the quarter-finals, knowing that playing Nadal in Roland Garros is always a physical battle," said Djokovic.

Adding an extra twist was a battle of wills over scheduling which Nadal lost Monday when organisers selected the quarter-final for the night session under the Court Philippe Chatrier lights.

"I don't like to play on clay during the night, because the humidity is higher, the ball is slower, and there can be very heavy conditions especially when it's cold," said Nadal.

Djokovic hinted he would prefer to face Nadal as late as possible.

"All I will say is Rafa and I would make different requests," he said.

Nadal's coach Carlos Moya said that the Spaniard's opinion should have carried weight.

"I wouldn't say disrespect, but here at Roland Garros, Rafa has credit," Moya told RMC Sport.

"He has won the tournament 13 times, and if he has a request, you should listen to him. He is part of the history of Roland Garros."

"But in the end, it is a question of business and we understand that."

Carlos Alcaraz, who faces Alexander Zverev, said it would have been "unfair" if he was ordered to play after 9pm for the third time.

- Alcaraz show -
Alcaraz, 19, is the youngest man to make the last-eight in Paris since Djokovic in 2006.

He boasts a 2022 claycourt record of 20 wins against just one loss. For the year, he is 32-3.

The sixth seed had to save a match point to defeat compatriot Albert Ramos-Vinolas in the second round but has otherwise been unburdened by expectations.

Alcaraz tackles third seeded Zverev having defeated the German in the final of the Madrid Masters where he also knocked out both Nadal and Djokovic.

Zverev added spice to the tie by claiming Alcaraz is being favoured by organisers who have given the teenager three matches out of four so far on Chatrier.

The Olympic champion described playing on Chatrier as "completely different" compared to other courts. "It's like playing on another continent."

While Djokovic, Nadal, Zverev and Alcaraz battle in the top of the draw, the bottom section has been blown wide open by the fourth round exits of second ranked Daniil Medvedev and number four Stefanos Tsitsipas, the 2021 runner-up.

As a result, one of Holger Rune, Casper Ruud, Andrey Rublev or Marin Cilic will make Sunday's final.