The 32-year-old international had been in isolation along with the rest of Serie A leaders' squad following teammate Daniele Rugani's positive test a week ago, with France's Blaise Matuidi also catching the virus in recent days.

Higuain had reportedly asked Juve for permission to visit his sick mother, and had a test confirming he was negative for COVID-19.

The recommended quarantine period is two weeks.

As flights to Argentina are all blocked, Higuain organised a transfer by private jet with his family first to France late on Wednesday, then Spain and from there fly to South America, Sky Sports Italia and Gazzetta Dello Sport reported. 

Germany's Sami Khedira and Bosnian Miralem Pjanic have also left Turin to join their families, Gazzetto reported. 

Star attacker Cristiano Ronaldo had remained in Portugal to self-isolate after his mother suffered a stroke.

Italy has been hard-hit by the coronavirus pandemic with over 3,000 deaths and more than 13,000 positive cases.