Lyon lurched further into crisis on Saturday as they went down 2-0 to Angers to ruin what was their last ever Ligue 1 match at the Stade de Gerland.
Cheikh N'Doye scored both goals for the visitors from headers either side of half-time as the promoted club built on a goalless draw at home to Paris Saint-Germain in midweek to continue their remarkable season.
But Lyon have now taken just one point from their last four league games and, coupled with their limp exit from the Champions League, that form has left coach Hubert Fournier under huge pressure.
OL president Jean-Michel Aulas has not been shy to express his displeasure with recent performances and this latest display was particularly painful as it came on such a special occasion for the club.
After 65 years at the Stade de Gerland, Lyon will move into a new 59,000-capacity stadium in January and a host of former players were invited to take to the field before kick-off in what was their final Ligue 1 outing at the old ground.
Brazilian duo Sonny Anderson and Juninho Pernambucano were among those present and watched the game alongside the Lyon ultras massed behind the goal.
But the match itself was further proof that all is not well at last season's runners-up.
Fournier pushed Mathieu Valbuena right up front alongside Alexandre Lacazette and handed a top-flight debut to teenager Lucas Tousart in midfield, and yet the changes could not prevent another catastrophic result.
Angers took the lead from their first chance just before the midway point in the first half, N'Doye rising high above Bakary Kone to head in a Thomas Mangani free-kick.
N'Doye then flashed another header just wide from a Gilles Sunu set-piece delivery and Anthony Lopes saved from Sunu to keep Lyon in the game going into the interval.
There was a response from the hosts after the restart and Valbuena crashed a shot off the bar before substitute Clement Grenier set up Lacazette to put the ball in the net only for the offside flag to cut short the celebrations.
And it was to be N'Doye who had the honour of scoring the last Ligue 1 goal at the old stadium as he made sure of the win for Angers with his and his side's second nine minutes from the end.
The 29-year-old Senegalese midfielder, who had never played in the top flight before this season, has been a revelation captaining the unfancied Angers.
At 1.92m tall and 90kg, he is a monster of a player, and yet he was left unchallenged to head in a corner from the left as Angers moved provisionally into second place.
Lyon, who will play one last game at Gerland in the League Cup later this month, are fourth but are likely to tumble down the table over the course of the weekend.
PSG are 15 points clear of Angers after continuing their unbeaten start to the domestic season with a 3-0 win at Nice on Friday.
Edinson Cavani put the capital club ahead before Zlatan Ibrahimovic netted twice, including one from the penalty spot, to become PSG's all-time leading scorer in the top flight with 87 goals.
Caen can reclaim second place with a win at home to Lille later on Saturday, while Monaco can go fourth with a win at Bastia.