Group A

At Istanbul, Turkey
Fenerbahce (TUR) 1 (Nani 42) Molde (NOR) 3 (Hoiland 36-pen, Elyounoussi 53, Linnes 65)

At Amsterdam
Ajax (NED) 2 (Fischer 25, Schone 84) Celtic (SCO) 2 (Biton 8, Lustig 42)

Group B

At Bordeaux, France
Bordeaux (FRA) 1 (Jussie 81) Liverpool (ENG) 1 (Lallana 65)

At Sion, Switzerland
Sion (SUI) 2 (Moussa Konate 11, 82) Rubin Kazan (RUS) 1 (Kanunnikov 65)

Group C

At Baku
Qabala FK (AZE) 0 PAOK (GRE) 0

At Dortmund, Germany
Dortmund (GER) 2 (Ginter 45+1, Park Joo-ho 90+2) FC Krasnodar (RUS) 1 (Mamaev 12)

Group D

At Herning, Denmark
Midtjylland (DEN) 1 (Kucharczyk 60-o.g.) Legia Warsaw (POL) 0

At Naples, Italy
Napoli (ITA) 5 (Callejon 5, 77, Mertens 19, 25, Hamsik 53) Club Brugge (BEL) 0

Group E

At Vienna
Rapid Vienna (AUT) 2 (Schwab 50, Hofmann 53-pen) Villarreal (ESP) 1 (Carrilho Baptistao 45)

At Pilsen, Czech Republic
Viktoria Plzen (CZE) 2 (Horava 36, Petrzela 75) Dinamo Minsk (BLR) 0

Group F

At Liberec, Czech Republic
Slovan Liberec (CZE) 0 Sporting Braga (POR) 1 (Rafa 60)

At Groningen, Netherlands 
FC Groningen (NED) 0 Marseille (FRA) 3 (Nkoudou 25, Ocampos 39, Alessandrini 61)

Group G

At Dnipropetrovsk
Dnipro (UKR) 1 (Seleznyov 90+4) Lazio (ITA) 1 
(Milinkovic-Savic 34)

At Saint-Etienne
Saint-Etienne (FRA) 2 (Beric 4, Roux 87-pen) Rosenborg (NOR) 2 (Mikkelsen 16, Svensson 79)

Group H

At Lisbon
Sporting Lisbon (POR) 1 (Montero 50) Lokomotiv Moscow (RUS) 3 (Samedov 12, 56, Niasse 65)

At Elbasan, Albania
Skenderbeu (ALB) 0 v Besiktas (TUR) 1 (Sosa 28)

Group I

At Florence, Italy
Fiorentina (ITA) 1 (Kalinic 4) Basel (SUI) 2 (B. Bjarnason 71, El Neney 79)

At Lech Poznan (POL) 0 Belenenses (POR) 0

Group J

At Brussels
Anderlecht (BEL) 1 (Gillet 11) Monaco (FRA) 1 (Traore 85)

At London
Tottenham Hotspur (ENG) 3 (Son Heung-min 28, 30, Lamela 86) Qarabag (AZE) 1 (Richard Almeida 7-pen)

Group K

At Nicosia
APOEL (CYP) 0 Schalke (GER) 3 (Matip 28, Huntelaar 35, 71)

At Tripoli, Greece
Asteras (GRE) 1 (Mazza 2) Sparta Prague (CZE) 1 (Lafata 56)

Group L

At Belgrade
Partizan Belgrade (SRB) 3 (Oumarou 11, 39, Zivkovic 89) AZ Alkmaar (NED) 2 (Jop van der Linden 34, Henriksen 90+3)

At Bilbao, Spain
Athletic Bilbao (ESP) 3 (Aduriz 55, 66, Susaeta 90) Augsburg (GER) 1 (Hal. Altintop 15)