Benjamin Pavard has tested positive for COVID-19, Bayern Munich have confirmed.
France international Pavard has begun self-isolating at home but the club said he was "in good health".
Bayern face Eintracht Frankfurt in the Bundesliga on Saturday before the first leg of their Champions League last-16 tie against Lazio in Rome next Tuesday.
Hansi Flick's side are unbeaten in their nine games without Pavard this season, winning seven of those matches and conceding just eight times.
Pavard has attempted 41 crosses from open play in the Bundesliga in 2020-21, with Lucas Hernandez the only Bayern defender to have more (44).
However, only five of Pavard's deliveries have found a team-mate, compared to 15 for Hernandez.
Leon Goretzka and Javi Martinez have not featured this month following positive coronavirus tests in January.
The duo, along with Serge Gnabry who has been dealing with a thigh issue, trained on Wednesday while the rest of the first team were granted a day off.