Gakpo's second spot kick in the 98th minute capped a remarkable ending at Icahn Stadium, which started with Guus Til being sent off three minutes before the full-time whistle. 

Uzbekistan made its man advantage count when Igor Sergeev netted a stoppage-time leveller, only for Gakpo to restore Netherlands's lead from the spot six minutes later. 

Netherlands started brightly and missed two glorious opportunities to open the scoring early on, the first of which saw Donyell Malen fire over the crossbar from close range. 

But after Jakhongir Urozov's poorly timed challenge on Crysencio Summerville inside the box, Gakpo squeezed the resulting spot-kick past Utkir Yusupov in the 32nd minute. 

Ronald Koeman's side continued to push after the break, with Virgil van Dijk heading narrowly wide before Brian Brobbey's goal was ruled out for a marginal offside.

However, Til was sent off for the denial of a goal-scoring opportunity after handling the ball outside the penalty area, though he also made contact with his hand inside the box, with referee Alyssa Pennington sending him off and awarding a free-kick after a VAR review. 

Uzbekistan thought it had snatched a draw when the ball broke kindly for Sergeev to prod home in the 92nd minute, but at the other end, Jan Paul van Hecke was pulled back inside the area from a corner by Abdukodir Khusanov, allowing Gakpo to step up and seal the win.