The Azzurri created a number of chances and saw a Jorginho penalty saved by Yann Sommer, who made seven saves in total at St. Jakob-Park.

It is the second stalemate in the space of three days for the recently crowned European champion, having also drawn 1-1 with Bulgaria in this week's World Cup qualifiers.

Despite dropping more points, Italy made it 36 games unbeaten to equal Brazil's all-time record, set between 1993 and 1996.

Mancini was once against disappointed with his side's profligacy in front of goal, however, as his side failed to find the net for the first time in 18 matches overall.

"This is a moment when the ball just isn't going in," he said. "Once again, we had too many chances not to win this game.

"It's not the penalty, it's other situations. We need to be more determined, more clinical, more precise. 

"Just like with Bulgaria, it's another match we cannot fail to win with that many scoring opportunities created.

"It was tougher in the second half, but we had the chances in the first half and the second, which means the team did play good football.

"The lads are tired, so there certainly will be some changes for the next game. It's a missed opportunity, exactly like on Thursday. Exactly the same."

That next game is against Lithuania in Reggio Emilia on Thursday (AEST), a game Italy will be overwhelming favourite to win no matter what side Mancini fields.

The draw leaves Italy four points clear of Switzerland, though the Group C second seed has two games in hand still to play.

With the sides set to face off again on Italian soil in two months' time, Mancini believes that showdown could well be a decider for the only automatic qualification spot.

"I think that will be the case, yes," he said.

Italy's run of draws spans four successive matches inside 90 minutes, though it won two of those matches on penalties on its way to Euro 2020 success.

Ten members of Italy's starting line-up were also part of the XI that helped brush aside Switzerland 3-0 in that tournament, with Emerson Palmieri for Leonardo Spinazzola the only change.

Skipper Giorgio Chiellini believes his side played better in Basel on Monday (AEST) than it did in that European Championship match two months ago.

"We played really well this evening in every sense, with technique and aggression, probably better than when we beat Switzerland 3-0 in June," he said.

"What we lacked was the little bit extra to score a goal. This is what we need to find as soon as possible, because this was already a big step forward from Thursday's game, as we were back to the team we saw at Wembley.

"We'll make another step forward for the Nations League in November, then we'll take World Cup qualification after that. 

"Let's take it one step at a time, recover some energy. There's a long way to go and we have to prepare for Wednesday."

Jorginho's penalty miss was his first for Italy from his sixth spot-kick, though that excludes shoot-outs, having also missed in the triumph over England in the Euros final.

"At that moment, it's the team that has to help Jorginho and we did," Chiellini added. "If we didn't have that bit of focus, we could've lost tonight and then made it really complicated for our qualification.

"There are many positives to be taken from this performance and we have to build on those."