WATCH: 10-man Inter stunned by Empoli at San Siro
Inter remained 13 points behind runaway leader Napoli after going down 1-0 at home following a first-half Milan Skriniar red card.
Empoli was good value for their win against Inzaghi's out-of-sorts side, and the head coach appeared to recognise that as he sought to move on swiftly from this match.
"We have to archive it immediately," he said. "We will have another difficult game, and we have to forget immediately, looking ahead.
"Of course, we will analyse the mistakes, but we have to think about the next matches."
The season is now at the halfway stage, and Inzaghi acknowledged Inter must improve.
"This is a defeat that stings," he said. "We finish the first half of the season with 37 points and many regrets.
"Now, we know we'll have to do better over the second part."
However, midfielder Hakan Calhanoglu is remaining optimistic, saying in an interview with Sky Sport: "Thirteen points [to Napoli] is a huge gap, but we have to keep going and not stop.
"I know it feels hard to believe, but there's still a long way to go."