Slipper will become just the 13th player to reach 100 Test appearances for Australia when he lines up in Brisbane on Saturday.

New Zealand have retained the Bledisloe Cup, which they have held since 2003, after last week's 43-5 victory.

While Slipper is set for a landmark appearance, the Wallabies have also named debutants Lachlan Swinton and Tom Wright to start and Angus Bell among the replacements.

"It's going to be a really special night for James in front of his family and friends back at his home ground and I know the team will be doing everything they can to make sure it's a memorable result," Australia coach Dave Rennie said.

"Lachlan, Tom and Angus have been excellent over the past seven weeks and have earned their first jersey for Australia through hard work and good performances. 

"As a whole group we were really disappointed after last weekend and we get a chance to show our character on Saturday in Brisbane."

Australia have lost only one of their past four Tests against New Zealand at Suncorp Stadium, winning two and drawing one.

The All Blacks, who top the Tri Nations table after the win last week, are set to see Whitelock reach a milestone.

Whitelock has been named to make his 100th Test start for New Zealand, becoming just the fifth player to reach that mark.

They have named Akira Ioane for a start on debut, while Asafo Aumua, Cullen Grace and Will Jordan are in line to make their first appearances off the bench.

"We've been really impressed with Akira. He's keen, he's ready and to have his first Test start is pretty special. I know Asafo is also excited for his first Test and he'll bring a lot of energy and enthusiasm when he comes off the bench," All Blacks head coach Ian Foster said.

"Cullen Grace is a young man who has also been very impressive. He's got a nice, quiet demeanour about him, but we know he's excited. Will Jordan has also been working really hard; he's settled in really, really well and he's got a calmness about him. He’s been doing a great job behind the scenes and we're delighted he's got his opportunity."

All Blacks star Beauden Barrett will start at number 10, with Damian McKenzie on the bench.

Australia: Tom Banks, Tom Wright, Jordan Petaia, Hunter Paisami, Marika Koroibete, Reece Hodge, Nic White; James Slipper, Brandon Paenga-Amosa, Allan Alaalatoa, Rob Simmons, Matt Philip, Lachlan Swinton, Michael Hooper, Harry Wilson.
Replacements: Folau Fainga'a, Angus Bell, Taniela Tupou, Ned Hanigan, Liam Wright, Tate McDermott, Noah Lolesio, Filipo Daugunu.

New Zealand: Jordie Barrett, Sevu Reece, Anton Lienert-Brown, Ngani Laumape, Rieko Ioane, Beauden Barrett, TJ Perenara; Karl Tu'inukuafe, Codie Taylor, Ofa Tuungafasi, Scott Barrett, Sam Whitelock, Akira Ioane, Sam Cane, Ardie Savea.
Replacements: Asafo Aumua, Alex Hodgman, Tyrel Lomax, Patrick Tuipulotu, Cullen Grace, Brad Weber, Damian McKenzie, Will Jordan.