It was a day that went from bad to worse for the Frenchman after being left out of the starting line-up for a second game running, only to see his team-mates fall four goals behind by the break, which led to his introduction in the second half.
Pogba lasted only 15 minutes as he was sent off by referee Anthony Taylor following a VAR review following a heavy challenge on Naby Keita.
The former Juventus man has experienced highs and lows since coming back to United from Italy in 2016, and rumours about his future persist as he gets closer to the end of his deal in Manchester, which expires at the end of this season.
There have also been questions raised about the relationship between Solskjaer and his players, especially following recent games in which the Red Devils have lost four and drawn one of their last five domestic fixtures.
However, Pogba took to Twitter on Wednesday to address a story published by The Sun which claimed that he had snubbed his manager in the dressing room following Sunday's defeat, and had also "shelved" contract talks.
The 28-year-old simply stated "Big lies to make headlines", and posted a screenshot of the story with a banner over the top saying "Fake news".
Pogba's agent Mino Raiola recently told The Times in an interview that there was "no update" on his client's future.
Before falling out of favour in recent games, the World Cup winner made a promising start to the season, and still sits at the top of the Premier League assist chart with seven, two ahead of Gabriel Jesus, Mateo Kovacic and Mohamed Salah.
He will be unable to add to those numbers for a while as he now misses games against Tottenham, Manchester City and Watford through suspension, with the trip to Chelsea on 28 November set to be the next match he will be available for.