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Neymar continued his stellar campaign with the opening goal inside nine minutes, but PSG was unable to extend its lead at the Stade du Moustoir.
Lorient's equalised eight minutes into the second half, with Terem Moffi firing home his ninth goal of the league campaign and then promptly hitting the bar.
It seemed that would be the closest either side came to a decisive second until Danilo rose highest from an 81st-minute Neymar corner to nod the winner.