Owen Farrell will be England's sole captain against Ireland, with Dylan Hartley unavailable for the start of the Six Nations due to injury.
Benetton Treviso continued its superb recent form in the Pro14 by handing Glasgow Warriors a third successive defeat that saw it leapfrogged at the top of Conference A by Munster.
Leinster had James Lowe sent off as its seven-game unbeaten Pro14 run was ended by rival Munster in an eventful derby clash at Thomond Park.
Leinster produced a sensational second-half comeback as Andrew Porter's try in added time clinched a thrilling 33-29 victory over Connacht.
Rory Scannell sealed a magnificent Munster comeback with a stunning 55-metre penalty beyond the 80th minute to clinch a 25-24 Pro14 victory over Glasgow Warriors at Thomond Park.
Ross Byrne produced a masterful kicking display as Leinster beat Munster 30-22 and Scarlets claimed a Pro14 derby win over Ospreys.