An ankle injury had sidelined Neymar since June and forced the Paris Saint-Germain forward to miss Brazil's successful Copa America campaign as he eyed a return to Barcelona.

Neymar, who was unable to engineer a Barca comeback before the transfer window closed, made his first appearance of the season for either club or country in Miami on Saturday (AEST), setting up Casemiro's opener before equalising in the 58th minute.

Luis Muriel's first-half brace cancelled out Casemiro's 19th-minute goal but Neymar came to the rescue 13 minutes into the second half as Tite's men extended their unbeaten run.

While Brazil welcomed back Neymar, Colombia was without James Rodriguez and Radamel Falcao, who joined Turkish giant Galatasaray prior to the transfer deadline, because of injury.

But Colombia made a lively start and was the better of the two teams as Juan Cuadrado and Yerry Mina came close to opening the scoring.

Neymar was relatively subdued in the first half however he provided the cross from a corner for Casemiro to head Brazil into a 19th-minute lead, the Real Madrid midfielder rising highest to beat David Ospina.

Brazil's lead was short-lived as Colombia equalised five minutes later through Muriel, who converted a penalty after being struck by Alex Sandro's high boot.

Richarlison had a good chance to restore Brazil's advantage but the Everton star's curling effort went just wide of the far post approaching the half-hour mark.

Colombia found the back of the net in the 30th minute but it was ruled out for offside, although it mattered little as Muriel struck four minutes later.

A great break from Roger Martinez saw Duvan Zapata receive the ball and play it out wide to Muriel, who fired past Brazil goalkeeper Ederson, before Ospina preserved Colombia's buffer by rushing out to thwart Richarlison.

Brazil returned to the pitch with renewed optimism and almost restored parity seven minutes into the second half but Philippe Coutinho's effort flashed just wide of the post after a terrific piece of skill to control the ball.

Coutinho was at the heart of the Selecao's 58th-minute equaliser after the Bayern Munich loanee picked out Dani Alves with a stunning pass from the halfway line as the latter squared a ball across the six-yard box for Neymar to side-foot into an empty net.

Next up, Brazil will face Peru in a rematch of the Copa America final on Wednesday, while Colombia meets Venezuela on the same day.