Last season's runner-up PSG were handed a trip to Ligue 2 Lorient, which plays on an artificial pitch, in Tuesday's (AEDT) draw.
Thomas Tuchel rested Neymar, Kylian Mbappe, Mauro Icardi and Keylor Navas but his team still ran out 6-0 winners against Linas-Montlhery in the round of 64 on Monday (AEDT).
Marseille only got past Trellisac on penalties and their reward was a trip to National 2 outfit Granville, while Lyon will travel to Nantes in an all-Ligue 1 clash.
A last-gasp goal from Keita Balde Diao in Robert Moreno's first game at the helm ensured Monaco remained in the hat. They will travel to fourth-tier side Saint-Pryve Saint Hilaire, conqueror of Toulouse in the previous round.
Reunion's Saint-Pierroise, the only overseas team left in the draw, were handed a trip to National 2 team Epinal after an 18,000-kilometre round trip to Niort ended with a shock 2-1 victory.