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The Lions of Teranga were beaten in the 2019 final by Algeria, but they belatedly got their hands on the trophy at Olembe Stadium with a dramatic shoot-out victory after a largely dour goalless 120 minutes.
See how the match unfolded LIVE
Mane saw an early penalty saved by Mohamed Abou Gabal and he was fortunate to still be on the pitch for the spot-kicks having avoided a second yellow card for a clear dive.
The Liverpool forward had the last laugh, though, powering low past Abou Gabal after Edouard Mendy had kept out Mohanad Lasheen's tepid effort from 12 yards to send the travelling Senegal fans into raptures.