Messi inspired his side in Buenos Aires on Wednesday (AEST), scoring a hat-trick and setting up Sergio Aguero for Argentina's fourth.

The Barcelona star's third was set up by Pavon, the substitute doing brilliantly down the left before cutting back for Messi to complete his hat-trick.

The duo's combination has impressed Sampaoli, who praised their connection after the convincing friendly win.

"Cristian is a player who has very special characteristics for communicating with Messi," he said.

"He goes to space, he is offering all the time and he has an important dynamic."

Also having an impact off the bench after being introduced on the hour-mark was Aguero, who got on the scoresheet having replaced Gonzalo Higuain.

"Aguero and Pavon came on very well," Sampaoli said.

"Haiti didn't have so many players behind the ball and that boosted their chances."

Argentina faces Israel in another friendly on 10 June before beginning its FIFA World Cup campaign against Iceland seven days later.