Zlatan Ibrahimovic was shown a straight red card for violent conduct in LA Galaxy's 1-0 MLS victory at Montreal Impact.
Bradley Wright-Phillips scored twice in the second half as New York Red Bulls rallied past Atlanta for their fourth consecutive win.
David Villa, 36, was the hero on Saturday as he helped end New York City's two-match winless streak.
Even without Sebastian Giovinco, Toronto managed to overcome Orlando City in MLS.
Orlando City have never qualified for the MLS play-offs but Yoshimar Yotun believes the Lions are poised to end their drought.
Zlatan Ibrahimovic has become the latest global superstar to join an MLS franchise.