Lucie Safarova was the latest seed to make an early exit at the US Open as Lesia Tsurenko booked her place in the second round at Flushing Meadows for the first time.

Five seeds were dumped out on the opening day of this year's final grand slam event – including Ana Ivanovic – and an out-of-sorts Safarova was powerless to avoid a similar outcome as she was beaten in straight sets.

The sixth seed had won the previous two meetings with Tsurenko and beat her in three sets recently in the Connecticut Open semi-final.

There was no repeat of that triumph on Tuesday, though, as the Ukrainian dominated their first-round encounter, progressing 6-4 6-1 in 65 minutes

Safarova – who reached the French Open final earlier this year – was immediately under pressure on her own serve as Tsurenko let an early break chance slip through her fingers.

Two games later she made no mistake as she broke to love, the second of four successive games won by the world number 37.

Tsurenko calmly served out to win the set and promptly dominated the second as she won four games in a row, her groundstrokes too good for her opponent.

Safarova eventually got herself on the board, but the damage was already done as a host of flowing forehands gave Tsurenko her first US Open triumph.