New Zealand will be without the experienced Simon Mannering for the upcoming Four Nations in England due to a knee injury.

Mannering did not take part in last weekend's 26-6 defeat against Australia in Perth in a bid to aid his recovery from the issue.

However, the forward, who has already been replaced as captain by Jesse Bromwich, has not been passed fit for the competition.

"He's up and running, but his knee isn't game ready," said New Zealand team doctor Greg Macleod in a statement.

"We have maintained regular contact with the New Zealand Warriors medical staff and we were optimistic that Simon would be ready for the tour. It turns out he needs a bit more time to make a full recovery."

Kiwis coach David Kidwell is disappointed to lose Mannering but is excited by the potential of his replacement, James Fisher-Harris of Penrith Panthers.

"Simon is a big loss for us. His leadership, experience and work ethic are really valuable, but I'm confident in my senior playing group to demonstrate those characteristics, on and off the field," said Kidwell.

"He [Fisher-Harris] was really high on our list for the initial squad, but narrowly missed out. We are fortunate to have this calibre of player to call on.

"He's come through the NZRL [New Zealand Rugby League] pathways and has performed at a very high level in the NRL. I'm looking forward to getting him in camp."