France and Lyon midfielder Nabil Fekir is set for a long stint on the sidelines after rupturing the ligaments in his right knee on international duty.

The 22-year-old midfielder lasted just 13 minutes of France's 1-0 friendly win over Portugal on Friday, with Fekir's fifth cap ending in misfortune as he pulled up in a fairly innocuous manner and had to be helped from the field.

The French Football Federation confirmed on Twitter after the match that Fekir had suffered a serious knee injury.

The Lyon academy graduate had a breakout season in 2014-15 alongside the likes of fellow youngsters Alexandre Lacazette, Clinton N'Jie and Jordan Ferri.

Fekir had extended that form into the new Ligue 1 season with four goals in as many matches for Lyon but reports claim he could now be out for at least six months.

Lacazette sent his club and national teammate condolences on Twitter, writing: "Big thoughts for my Frero... @Nabilon69 You'll come back stronger."