Manchester United will face Celta Vigo in the semi-finals of the UEFA Europa League, while Ajax was paired with Lyon in Friday's draw.
United needed an extra-time winner from teenager Marcus Rashford to progress 3-2 on aggregate against Anderlecht, while Celta beat Genk to progress to the last four.
The second leg will be played at Old Trafford.
In the other semi-final tie, knocking out Besiktas on penalties has earned Lyon the chance to take on Ajax, with the first leg to be played at the Amsterdam ArenA on 5 May (AEST).
With the winners f the UEFA Europa League earning a qualifying spot in next season's UEFA Champions League, all four clubs will be keen to secure a place in the 25 May (AEST) final at the Friends Arena in Sweden.